Job responsibilities:

1、Full accountability for in-house computing infrastructure, external computing resources, IoT/IT setup and security.

2、Leading accountability for hardware environment, software implementation, system upgrades, maintenance, and scheduling management.

3、Independent accountability for staying up to date in mandatory fields of expertise, and for the advancement of AIDD computing environment. 

4、Routine accountability for regular guidance and on-demand support to the AIDD team, and to GenHouse affiliates.

Job requirements:

1、MS/PhD in computer science/engineering with a track record in physics and mathematics, or MS/PhD in physics/mathematics with hands-on experience of IoT and IT, is preferred.

2、BS in a comparable field with a certificate or proven track record in systems administration will also be considered.

3、Advantageous experience: management of HPC, batch scheduling, cloud computing, GPU coding, and a strong programming background using Linux operating systems.

4、Additional skills: NLP, data engineering, statistical computing.

5、Self-motivation, an open mindset, the hunger for innovation, and the thirst to translate new ideas into reality in the blink of an eye.

 

Job responsibilities:

1、Full accountability for chemical modeling and management of virtual libraries.

2、Leading accountability for the building of proprietary chemical databases and ligand-based drug design (LBDD).

3、Independent accountability for staying up to date in mandatory fields of expertise, method implementations, project applications, and corresponding advancement of the AIDD platform. 

4、Routine accountability for regular guidance and on-demand support to the AIDD team, and to GenHouse affiliates.

Job requirements:

1、PhD with a computational focus on physical chemistry, medicinal chemistry, biochemistry, or bioengineering, is preferred.

2、MS in a comparable field with an outstanding track record will also be considered.

3、Desired expertise: empirical/statistical modeling of chemical structures, ensemble similarity, retro-synthesis, physicochemical properties, PK/PD properties, and coding in a Linux operating system.

4、Advantageous experience: use of MOE, KNIME, ChemAxon, OpenEye, or an unlisted major package of cheminformatics and LBDD.

5、Additional skills: workflow automation, data engineering, virtual screening.

6、Self-motivation, an open mindset, the hunger for innovation, and the thirst to translate new ideas into reality in the blink of an eye. 

 

Job responsibilities:

1、Full accountability for protein modeling and molecular dynamics simulations.

2、Leading accountability for structural bioinformatics and structure-based drug design (SBDD).

3、Independent accountability for staying up to date in mandatory fields of expertise, method implementations, project applications, and corresponding advancement of the AIDD platform. 

4、Routine accountability for regular guidance and on-demand support to the AIDD team, and to GenHouse affiliates.

Job requirements:

1、PhD with a focus on computational chemistry and/or biophysics is preferred.

2、MS in a comparable field with a strong track record in atomistic molecular dynamics simulations will also be considered.

3、Desired expertise: protein modeling, enhanced sampling simulations, affinity prediction (molecular docking, TI, FEP), SBDD, and coding in a Linux operating system.

4、Advantageous experience: use of AMBER, GROMACS, NAMD, MOE, AutoDock Vina, smina, X-score, or an unlisted major package of computational chemistry and SBDD.

5、Additional skills: workflow automation, ensemble conformational analysis, dimensionality reduction.

6、Self-motivation, an open mindset, the hunger for innovation, and the thirst to translate new ideas into reality in the blink of an eye. 

Job responsibilities:

1、 Responsible for new drug R & D project management: closely following the global R & D hot spots. Move project forward from project initiation (based on potential market analysis, literature research, target screening, competitive product analysis and patent breakthrough), to drug molecular design, lead optimization, combining knowledge from comprehensive analysis of PK, PD research results and clinical information of competitive products, to complete the optimization iteration of active compounds, and advance the project to PCC stage efficiently；

2、 Responsible for the management of pharmaceutical and chemical project set: design the work plan, allocate work load and track the progress of drug R & D projects; Lead and motivate all project teams to accomplish tasks efficiently with high quality；

3、 Responsible for team performance review and team building regularly；

4、 Assist the director of pharmacy in completing the professional evaluation of the imported project, assist in tracking the progress and confirming acceptance of outsourcing projects；

5、 Actively follow up the frontier and hot spots of drug research and update the progress report regularly.

Job requirements:

1、 Doctor degree in organic synthesis or pharmaceutical chemistry, more than three years working experience；

2、 Familiar with drug R & D process, with solid ability of new compound design, SAR and SPR research, able to undertake research independently；

3、 Strong team management ability and problem-solving ability. Experience in team management and inter departmental communication is preferred；

4、 Strong sense of responsibility, honest and trustworthy, practical working attitude, good communication skills and teamwork spirit.

Job responsibilities:

1、 Conduct structure-activity relationship studies relatively independently under the guidance of pharmaceutical experts to discover, design and optimize lead compounds;

2、 To carry out the research and development of new drug projects, monitor the progress of the projects, analyze and solve the problems in the process of project advancement;

3、 Familiar with basic biology knowledge, able to interpret biological activity data and pharmacokinetic parameters, understand the basic process of new drug development；

4、 Participate in the collection and tracking of industry research and development information of the drug project in charge; Participate in new drug project research and feasibility analysis；

5、 Regularly summarize and report the project progress；

6、 Guide the subordinate staff to complete the experiment operation, complete the experiment record and report clearly and completely, and make it precise, detailed and reliable；

7、 Able to independently complete various complex organic chemical reaction operations, and can assist subordinates when necessary, assist internal chemists and external FTE team to complete the efficient synthesis of the designed molecules.

Job requirements:

1、 Ph. D. or master degree in chemistry or pharmaceutical chemistry or related field from a key university with more than 5 years relevant working experience;

2、 Experience in leading a team and solid knowledge of organic synthesis;

3、 Under the guidance of pharmaceutical experts, able to quickly master the new knowledge of pharmaceutical chemistry;

4、 Good sense of responsibility, industrious and pragmatic, serious and rigorous work, meticulous, proactive, full of team spirit, good coordination and communication skills and work execution ability;

5、 Pharmaceutical chemistry experience, CRO working experience is preferred.

Job responsibilities:

1、 Assist the research and development director, and responsible for the management of new drug research and development projects in the laboratory；

2、 Design synthetic route, lead the team members to efficiently complete the target compound synthesis work. Complete the optimization iteration of active compounds based on the comprehensive analysis of the research results,；

3、 Solve the pain points and difficulties in compound synthesis；

4、 Formulate work plan and task allocation, track progress of the drug research and development team in the laboratory; Lead and motivate the team to efficiently complete project tasks, responsible for team performance assessment, and regularly carry out team building and related training；

5、 Complete patent and article writing, relevant experience is preferred；

6、 Responsible for safety, hygiene and 5S management of the laboratory.

Job requirements:

1、 Ph. D. degree in organic synthesis, pharmaceutical chemistry or related field with 3 + years working experience or master's degree with 7 + years working experience in related field, the above requirements can be flexible if the ability is outstanding；

2、 Familiar with drug research and development process, with solid ability of compound synthesis route design and development, and able to manage the team to achieve the project milestones；

3、 Strong team coordination and management skills, analysis and problem solving skills, team management experience is preferred；

4、 Strong sense of responsibility, honest and trustworthy, steadfast working attitude, good communication skills and team spirit.

Job responsibilities:

1、 Design and optimize the synthesis route of the target molecule;

2、 Lead the team to complete the project tasks and track the progress of the project；

3、 Mentor team members on chemical knowledge and skills.

Job requirements:

1、 Major in pharmaceutical chemistry or organic synthesis, with solid theoretical knowledge of organic synthesis and related work experience, at least 2 years for master's degree, at least 5 years for bachelor's degree；

2、 Capable of innovation, and search, investigation and analysis of literatures skillfully using SciFinder and Reaxy to design synthesis routes of target objects；

3、 Synthesis, separation and structure identification skills are required ；

4、 Good communication, planning and execution skills, able to guide 3-5 people to complete 2-3 projects within the specified time, and proficient in writing project reports in English；

5、 Have a strong sense of responsibility, team spirit and hard-working spirit.

Job responsibilities:

1、 Cooperate with supervisor to carry out, coordinate, manage and execute the API related work of innovative drug；

2、 Responsible for the development of innovative drug synthesis process, impurity research, pilot scale and production verification；

3、 Coordinate and solve technical problems in the process of project research；

4、 Responsible for the preparation of research project plan and report, application materials and other documents；

5、 Reasonable for budget control of process development；

6、 Cooperate with the research group to formulate regional safety and health work.

Job requirements:

1、 Master degree in organic chemistry, drug synthesis, etc., more than 3 years of API process research experience；

2、 Familiar with the research and development ideas and processes of drug synthesis technology, able to control the overall progress and key nodes of the project；

3、 Familiar with domestic and foreign regulations and application of drug research；

4、 Have strong document retrieval ability and a certain level of English, can independently search foreign language materials；

5、 Have certain project management ability, have good communication and coordination ability；

6、 Experience in team management and project management is preferred. Work steadfast, dedicated, rigorous.

Job responsibilities:

1、 Responsible for the formulation research of new drugs: collect and sort out domestic and foreign pharmaceutical research trends, familiar with new drug R&D process, and formulation related regulatory requirements；

2、 Responsible for the implementation of formulation development, technical development, participate in the formulation technology development to tackle key problems, solve technical problems；

3、 According to the company's overall R&D project plan, participate in the design of project formulation R&D plan and coordinate the implementation of the plan, analyze and solve the problems in the R&D process in time；

4、 Lead technical personnel to complete drug formulation design, screening and process research, including dosage form design, laboratory scale test process development, pilot scale test process development and other new drug related research；

5、 According to the requirements of drug registration and approval, write related application materials and original records and answer questions about formulation research raised by reviewers；

6、 Solve the difficulties and related technical problems in the process of trial production, and scale-up production.

Job requirements:

1、 Master degree or above in pharmaceutical formulation or pharmacy related field；

2、 At least 3-year experience in drug formulation design, screening and process research and development, including dosage form design, laboratory scale test process development, pilot scale test process development and other new drug related research；

3、 Familiar with the technical guidelines for drug development, and familiar with the development process and requirements for complex drug formulation or injection；

4、 Familiar with R&D and production equipment of various dosage forms, solid, liquid, sterile, injection formula development experiences are preferred；

5、 Have formulation project research and development management ability, capable of carrying out the planning, review, management, implementation and quality control of formulation projects；

6、 Capable of writing and review application materials, familiar with the format of CTD application materials, understand the requirements of technical review at the present stage.