Genhouse Announces Global Partnership on its MAT2A Inhibitor Synthetic Lethality Therapy GH31 with Gilead

 2026-02-13

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[SUZHOU, China | February 13, 2026] —Suzhou Genhouse Bio Co., Ltd. (Genhouse), a China-based biotech company focused on innovative oncology therapies, today announced that it has entered into a definitive agreement with Gilead Sciences, Inc. (Nasdaq: GILD) (Gilead) for GH31, an IND-cleared synthetic lethality oncology program developed by Genhouse.

 

Under the terms of the agreement, Gilead will gain the worldwide rights to develop and commercialize GH31. Genhouse will receive an $80 million upfront payment and is eligible to receive additional milestone payments associated with development, regulatory, and commercialization milestones of up to $1.45 billion, as well as tiered royalties on net sales up to low double digits.

 

GH31 is a biomarker-driven synthetic lethality therapy targeting MAT2A, with potential application across multiple tumor types. The program has received IND clearance in the United States and China, enabling immediate advancement into global clinical development. Gilead will assume full global responsibility for GH31, including development, regulatory submissions and future commercialization.

 

"This transaction represents a significant value-realization milestone for Genhouse and highlights the global attractiveness of our synthetic lethality innovation," said Dr. Kuifeng Wang, CEO of Genhouse. "With IND clearance in hand, GH31 is well positioned for rapid clinical advancement, and we believe Gilead is ideally suited to maximize its global potential for patients."

 

"The addition of GH31 reflects our disciplined approach to expanding Gilead’s oncology pipeline through innovative science and strong partnerships," said Jackson Egen, Senior Vice President Oncology Research, Gilead Sciences. "We are excited to partner with Genhouse to unlock the full global potential of this program."

 

About Genhouse

Suzhou Genhouse Bio Co., Ltd. is a clinical-stage biotech company based in China dedicated to the discovery and development of innovative therapies for cancer. The company leverages its combination of research platforms to advance a pipeline of differentiated drug candidates for global markets.

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